acute myelogenous leukemia, aml, adult…

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auer rods, acute monocytic leukemia, skin, blood cells, aml, acute myeloid leukemia, aml, acute granulocytic leukemia, acute nonlymphocytic leukemia, anll, leukemia, acute myeloid, aml, leukemia, acute granulocytic, leukemia, nonlymphocyctic, anll, acute myelogenous leukemia, cancer of blood-forming tissues, the bone marrow, characterized by the growth, immature white blood cells, 8 categories of aml, categorized, m0 to m7, which blood cells, abnormal, acute myelogenous leukemia, aml, occur at any age, primarily affects adults, children younger than one year old, discussion focuses on aml in adults, certain blood cells, the immune system, grow, in the bone marrow, lose ability to mature, specialize, differentiate, cells multiply rapidly, replace normal blood cells, bone marrow failure occurs, malignant cells replace normal bone marrow, patients, aml, susceptible to bleeding, infection, the normal blood cells lose ability to fight microorganisms, decrease in number, most cases have no apparent cause, radiation, toxins benzene, chemotherapy drugs, etoposide, drugs known, alkylating agents, thought to cause some kinds of leukemia, aml, genetic abnormalities, play a role, in the development of this condition, risk factors, exposure to radiation, chemicals, immunosuppression following organ transplantation, blood disorders, myeloproliferative diseases polycythemia vera, essential thrombocythemia, myelodysplasia, refractory anemia, prolonged bleeding, bruising, bleeding gums, bleeding, nose, menstrual periods, abnormal, skin rash, lesion, fatigue, fever, bone pain, tenderness, weight loss, swollen gums, rare, shortness of breath aggravated by exercise, paleness, a physical examination, evidence of anemia, pallor, bleeding, less commonly an enlarged spleen, liver, enlarged lymph nodes found, a wbc count, a cbc test shows anemia, low platelet count, a bone marrow aspiration shows evidence of leukemic cells, objective of treatment, eliminate the cancer cells, chemotherapy, unfortunately, process also eliminates normal cells that present, in the bone marrow, treatment the patient is at risk, excessive bleeding, low numbers of platelets, infection, a low white blood count, takes several weeks, the bone marrow to recover, start producing normal cells, time supportive care is intensive, consists of patient isolation, prevent infection, antibiotics to treat infection, transfusions of platelets to control bleeding, red blood cell transfusions to combat anemia, after remission is achieved, further treatment is known, consolidation, achieve a permanent cure, consolidation, consist of either further chemotherapy, a bone marrow transplant, a stem cell transplant, transplants, used in patients, relapsed disease, the different subtypes of aml have similar treatment, differences, in the treatment of one type of leukemia known, acute promyelocytic leukemia, apl, in this type of leukemia, this type, a medicine, all-trans retinoic acid, atra, cause the leukemia cells to mature into normal white blood cellss, atra is used, remission, consolidation treatments, has increased the cure rate, type of aml, additionally, drug arsenic trioxide is approved, use in patients, apl, failed treatment, atra, usual chemotherapy, achieve first remission, later relapse, newer treatments, aml include monoclonal antibodies, experimental drugs given in clinical trials, cancer support group, leukemia support group, complete remission occurs in 70-80% of patients, 20-30% of people survive free of disease at 5 years from diagnosis, patients, not experienced a relapse, considered permanently cured, most relapses occur, 2 years of diagnosis, under 60 years of age have a better chance of survival than older counterparts, related to many factors, the ability to tolerate the strong chemotherapy medicines, life expectancy, 3 to 4 months, relapse, severe infection, life-threatening bleeding, develop symptoms of aml, persistent fever, signs of infection occur, aml, get protection from any work-related exposure to agents associated, the development of acute leukemia, minimize radiation exposure.