congenital afibrinogenemia…

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congenital afibrinogenemia, rare, inherited blood disorder, the blood, does not clot, due to a lack of, a malfunction involving fibrinogen, a protein necessary, coagulation, this rare disease, an autosomal recessive gene, inheritance, the abnormal gene from both parents, either a complete lack of fibrinogen, a defect, in the functioning of available fibrinogen, occur in both sexes, main risk factor, family history of bleeding disorders, bruising, nosebleeds, excessive bleeding following injury, surgery, gastrointestinal bleeding, bleeding in joints, miscarriage, , a bleeding disorder is suspected, laboratory tests, the type, extent, shows up in childhood, at birth, ptt, prothrombin time, pt, clotting time, fibrinogen levels, thrombin time, reptilase time, bleeding time, all of these tests, abnormal in afibrinogenemia, patients transfused, plasma, liquid portion, the blood, cryoprecipitate, a blood product containing concentrated fibrinogen, to treat bleeding episodes, in preparation, surgery needed to treat other conditions, immunized, the hepatitis b vaccine, the increased risk of developing hepatitis, due to transfusion, significant bleeding is common, episodes severe, fatal, bleeding, in the brain, leading cause of death in patients, , bleeding, umbilical cord, bleeding, mucous membranes, gastrointestinal bleeding, intracranial bleeding, clotting, development of antibodies, inhibitors, to fibrinogen, call health care provider, seek emergency care, excessive bleeding occurs, notify surgeon, have surgery, suspect have a blood disorder, , no known prevention, couples, at least one partner has this condition, find genetic counseling helpful, considering having children.