congenital hypothyroidism…

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thyroid gland, cretinism, congenital hypothyroidism describes a newborn, decreased, very rarely, absent, thyroid hormone production, hypothyroidism, in the newborn, result from absence of, abnormal development, the thyroid gland, destruction, the thyroid gland, failure of stimulation, the thyroid by the pituitary, by defective, abnormal synthesis of thyroid hormones, incomplete development, the thyroid, most common defect, occurs at a rate of 1 out of every 3,000 births, girls, twice, affected than boys, most affected infants have little, no symptoms, they only have a mild deficiency of thyroid hormone, infants, profoundly hypothyroid often have a distinctive appearance, a puffy-appearing face, a dull look, a large tongue that protrudes, mouth, kept open, develop this appearance, the disease progresses, brittle hair, low hairline, jaundice, feeding is poor, infant, choke frequently, constipation is common, children, not cry, sleep excessively, sluggish, inactive, muscle tone, decreased, untreated, mild hypothyroidism, lead to severe mental retardation, growth retardation, development is delayed early on, indicated by failure to meet normal milestones, appearance of teeth delayed, become more severe, the child ages, growth failure in terms of body length is noted very early, floppy infant, thick, protruding tongue, poor feeding, choking episodes, constipation, prolonged jaundice, short stature, sutures, separated widely, a large posterior fontanelle, large fontanelle, posterior fontanelle, soft spots, dull-appearing facial features, dry, brittle hair, low hairline, short, thick neck, growth failure, short extremities, broad hands, short fingers, myxedema, hypotonia, hoarse-sounding cry, voice, x-ray, the long bones, free, unbound, t4, thyroxine, levels, serum tsh level, serum tbg level, total thyroxine values, measured, thyroid scan, technetium, early diagnosis is imperative, the effects of hypothyroidism, reversible, critical development, the nervous system takes place, in the first few months after birth, thyroid hormone deficiency, irreversible damage, nervous system, marked mental retardation, replacement therapy, thyroxine, standard approach to treatment of hypothyroidism, once medication starts, blood levels of tsh, free t4, monitored to keep the values, a normal range, very early diagnosis generally results, good outcome, the infant, in terms of growth, mental capability, newborns diagnosed, in the first month to month, a half generally develop normal intelligence, absence of thyroid hormone, early life gives a poor outlook in terms of mental development, mental retardation, growth retardation, child shows signs, symptoms of hypothyroidism, pregnant, exposed to antithyroid drugs, have signs, symptoms of hypothyroidism, absence, the thyroid, defective thyroxine production, not preventable, destruction, the thyroid, in the fetus, occur mother is treated, radioactive iodine, thyroid cancer she is pregnant, infants of mothers taking antithyroid medications, observed after birth, evidence of drug induced transient, brief, hypothyroidism, most states mandate a routing screening test on all newborns to detect hypothyroidism.