dexamethasone suppression test…

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what the risks are dst, acth suppression test, cortisol suppression test, dexamethasone suppression test measures the response, the adrenal glands to acth, dexamethasone is given, levels of cortisol, measured, cortisol levels should decrease in response, administration of dexamethasone, two different types of dexamethasone suppression tests, low-dose test, high-dose test, each type, either be done in an overnight, standard, 3-day, way, the low-dose overnight method, 1 mg of dexamethasone is given at 11 p, m, blood is drawn at 8 a, m, cortisol measurement, venipuncture, standard low-dose method, urine is collected at 24-hour intervals over 3 days, measurement of cortisol, on day 2, a low dose, 0.5 mg, dexamethasone is given by mouth every 6 hours, 48 hours, the high-dose overnight method, a baseline cortisol is measured on the morning, 8 mg of dexamethasone is given at 11 p, m, blood is drawn at 8 a, m, cortisol measurement, the standard high-dose test, urine is collected at 24-hour intervals over 3 days, measurement of cortisol, on day 2, a high dose, 2 mg, dexamethasone is given by mouth every 6 hours, 48 hours, health care provider, advise to discontinue drugs, affect the test, drugs, affect test results include barbiturates, estrogens, corticosteroids, oral contraceptives, phenytoin, spironolactone, tetracyclines, infants, children, test depends on child's age, level of trust, prepare child, infant test, procedure preparation, birth to 1 year, toddler test, procedure preparation, 1 to 3 years, preschooler test, procedure preparation, 3 to 6 years, schoolage test, procedure preparation, 6 to 12 years, adolescent test, procedure preparation, 12 to 18 years, the needle is inserted to draw blood, feel moderate pain, others feel only a prick, stinging sensation, some throbbing, this test is performed, overproduction of cortisol is suspected, low-dose test, differentiate healthy people from those who produce too much cortisol, high-dose test, determine abnormality, in the pituitary gland, cushing's disease, secretion of acth, pituitary gland, regulated by the level of cortisol, in the blood plasma, acth stimulates the adrenal cortex to produce cortisol, plasma cortisol levels increase, acth secretion is suppressed, cortisol levels decrease, acth increases, dexamethasone, synthetic steroid similar to cortisol, suppresses acth secretion in normal people, giving dexamethasone should reduce acth levels, resulting in decreased cortisol levels, pituitary glands which produce too much acth, have an abnormal response, low-dose test, a normal response, high dose, low dose, overnight, plasma cortisol < 5 mcg/dl, standard, urinary free cortisol on day 3 < 10 mcg/day, high dose, overnight, > 50 % reduction in plasma cortisol, standard, > 90% reduction in urinary free cortisol, normal value ranges, among different laboratories, not a normal response on the low-dose test, abnormal secretion of cortisol is likely, cushing's syndrome, could be a result of a cortisol-producing adrenal tumor, a pituitary tumor that produces acth, a tumor, in the body that inappropriately produces acth, high-dose test, distinguish a pituitary cause, cushing's disease, others, cushing's syndrome, adrenal tumor, low dose, no change, high dose, no change, cushing's syndrome related to ectopic acth-producing tumor, low dose, no change, high dose, no change, cushing's syndrome, pituitary tumor, cushing's disease, low dose, no change, high dose, normal suppression, excessive bleeding, fainting, feeling lightheaded, hematoma, blood accumulating under the skin, infection, a slight risk, the skin is broken, multiple punctures to locate veins, none.