drug-induced lupus erythematosus…

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lupus, discoid, view of lesions on the chest, lupus, discoid on a child's face, lupus, discoid on the face, antibodies, lupus erythematosus, chronic, inflammatory autoimmune disorder, affect the skin, joints, kidneys, organs, drug-induced lupus is caused, adverse, bad) reaction to a medication, drug-induced lupus erythematosus resembles systemic lupus erythematosus, sle, occurs, a result of a hypersensitivity reaction to a medication, drug, react, cell materials, causing the body to react to, form antinuclear antibodies, antibodies against structures, in the body's own cells, several medications, known to cause drug-induced lupus, procainamide, isoniazid, chlorpromazine, penicillamine, sulfasalazine, hydralazine, methyldopa, quinidine, symptoms tend to occur after taking the drug, at least 3 to 6 months, in drug-induced lupus erythematosus, features of arthritis, systemic symptoms, cardiac, pulmonary, lung, symptoms present, symptoms associated, sle, lupus nephritis, neurological disease, rare, drug-induced lupus erythematosus, severe, sle, symptoms go away, a few days to weeks after stopping the medication, drug-induced lupus affects men, women equally, sex distribution of drug-induced lupus erythematosus is equal, whereas in sle, women, affected more often than men, fever, loss of appetite, general discomfort, uneasiness, ill feeling, malaise, weight loss, skin rash, malar "butterfly" rash, skin rash aggravated by sunlight, joint pain, joint swelling, blurring vision, pleuritic chest pain, history shows use of a medication associated, drug-induced lupus, an examination, the skin shows characteristic skin rash, lesions, signs of pericarditis present, listening, chest, a stethoscope, auscultation, reveal abnormal sounds heart murmur, pleural friction rub, pericardial friction rub, sle, antinuclear antibody, ana, panel, lupus erythematosus cell test, rarely performed nowadays, anti-histone antibody, positive in drug-induced lupus, a histone, protein commonly found, in the cell's nucleus, a chest x-ray, evidence of pleuritis, pericarditis, an ecg, heart involvement, symptoms resolve, several days to weeks after stopping the medication that caused the symptoms, nonsteroidal anti-inflammatory medications, treat arthritis, pleurisy, corticosteroid creams, treat skin rashes, antimalarial drugs, hydroxychloroquine, used, skin, arthritis symptoms, sensitivity to light is treated by protective clothing, sunglasses, sunscreen, routine eye examinations, recommended to detect eye complications early, steroid prednisone, treat more severe cases, heart is involved, very rarely, severe drug-induced lupus, severe cardiac involvement, significant kidney, neurologic disease, high doses of steroids, strong medications that suppress the immune system, azathioprine, cyclophosphamide, resolve, several days to weeks after stopping the medication, essential not to restart the culprit medication at a later time, recur, abnormal antibodies, persist, years despite remission, infection, thrombocytopenia purpura, bleeding near the skin surface, resulting from a low number of platelets, in the blood, hemolytic anemia, myocarditis, pericarditis, not improve after discontinuing the medication that caused the symptoms, should also call if new symptoms develop, aware, the risk, taking medications, known to cause this reaction, symptoms begin to appear, consult health care provider, the advisability of changing medication, harris ed, budd rc, genovese mc, firestein gs, sargent js, sledge cb, kelley's textbook of rheumatology, 7th ed, wb saunders, 1183, 1598, noble j, textbook of primary care medicine, 3rd ed, mosby, 1270.