dubin-johnson syndrome…

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digestive system organs, dubin-johnson syndrome, inherited disorder characterized by mild jaundice throughout life, dubin-johnson syndrome, very rare autosomal recessive disorder, inherit the condition, a child must get a copy, the defective gene from both parents, transport of bilirubin, liver is dysfunctional, bilirubrin, product, the liver's metabolism of worn-out red blood cells, sent, digestive system, bilirubin is not properly processed, builds up, in the bloodstream, skin, the eyes take on a yellow tinge, severely high levels, damage the brain, organs, dubin-johnson syndrome have life-long low-grade jaundice that aggravated by alcohol, pregnancy, oral contraceptive use, infection, environmental factors that affect the liver, mild jaundice, not appear, puberty, adulthood, symptom of dubin-johnson syndrome, tests that abnormal, serum bilirubin, urinary coproporphyrin levels, mostly coproporphyrin i in dubin-johnson patients versus coproporphyrin iii in normal subjects, liver biopsy, no specific treatment, prognosis, condition is very positive, dubin-johnson syndrome generally, does not shorten the patient's life span, complications, unusual but, severe jaundice, reduced liver function, any, occurs, jaundice is severe, jaundice progressively worsens, abdominal pain, indicate another disorder is causing the jaundice, genetic counseling valuable, prospective parents, a family history of dubin-johnson syndrome.