gestational trophoblastic disease…

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chorioblastoma, choriocarcinoma, trophoblastic tumor, chorioepithelioma, invasive/malignant mole, gestational trophoblastic neoplasia, gestational trophoblastic disease, choriocarcinoma, an aggressive, malignant, metastatic, spreading, cancer, in the uterus that begins following a pregnancy, a miscarriage, an abortion, choriocarciona is among the most sensitive cancers to chemotherapy, such, choriocarcinoma is metastatic, cure rate is between 90, 95%, hydatidiform mole, condition which develops, a pregnancy has many complications, conception takes place, placental tissue grows very fast, rather than supporting the growth, a fetus, tumor, rather than a baby, a molar pregnancy, 3,000 molar preganancies per year, choriocarcinoma, similar type of growth, in approximately one-half of cases of choriocarcinoma, preceding factor is hydatidiform mole, 5, 10% of molar pregnancies, later choriocarcinoma, choriocarcinoma remains an uncommon, yet always curable, cancer, associated, pregnancy, nearly one-fourth of choriocarcinomas follow a term pregnancy from which a normal child has been delivered, remainder follow an abortion, spontaneous, elective, therapeutic, ectopic pregnancy, genital tumor, a possible symptom is continued vaginal bleeding, woman, a recent history of hydatidiform mole, abortion, term pregnancy, additional symptoms that associated, irregular vaginal bleeding, theca lutein cysts on the ovaries, unenlargement, the uterus, persistently elevated hcg, pregnancy hormone, levels, pain, symptoms related, disease spreading to other organs lungs, liver, brain, a pelvic examination, reveal continued uterine enlargement, a tumor, conditions felt, the genito-urinary tract, quantitative serum hcg, blood test to confirm pregnancy, ct scan to detect potential metastatic tumor in any organ, chest x-ray, signs, tests apply to women, a recent history of hydatidiform mole, abortion, term pregnancy, after an initial diagnosis, a careful history, examination, rule out metastasis, spread to other organs, chemotherapy, treatment of choice, a hysterectomy is rarely required, due to choriocarcinoma's extreme sensitivity to chemotherapy, than 90% of women, malignant, nonmetastatic disease, able to maintain reproductive capabilities, cancer resources, nearly all women, malignant, nonmetastatic disease, cured, more than 90% preserving reproductive function, women, malignant, metastatic disease, poor prognosis, they meet one, disease has spread, liver, brain, serum hcg measurement is greater than 40,000 miu/ml, time treatment is started, having received prior chemotherapy, having symptoms, preceding pregnancy, more than 4 months, term pregnancy is associated, diagnosis, 66% of women having a poor prognosis experience remission, a disease-free state, all women who receive a good prognosis, malignant, metastatic disease, does not meet one of these conditions experience remission, choriocarcinoma, recur, several months but possibly, 3 years after treatment ends, complications associated, chemotherapy, surgery, a hysterectomy is performed, infertility, menopause, begin ovaries, removed, symptoms arise, 1 year after hydatidiform mole, abortion, miscarriage, term pregnancy, careful monitoring, removal of hydatidiform mole, termination of pregnancy, prevent the development of choriocarcinoma, essential in early identification, improves outcome.