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glucose-6-phosphate dehydrogenase deficiency
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blood cells, g-6-pd deficiency, hemolytic anemia, due to g6pd deficiency, anemia, hemolytic, due to g6pd deficiency, g-6-pd deficiency, hereditary, sex-linked enzyme defect that results, in the breakdown of red blood cells, the person is exposed, stress of infection, certain drugs, g-6-pd deficiency, inheritable, x-linked recessive disorder whose primary effect, reduction, the enzyme g-6-pd in red blood cells, causing destruction, the cells, hemolysis, ultimately, hemolysis leads to anemia, either acute hemolytic, a chronic spherocytic type, united states, many more black than white people have the disorder, 10-14%, the black male population is affected, occasionally affect a black women to a mild degree, depending on genetic inheritance, the disorder, anemic, display no evidence, red blood cells, exposed to an oxidant, stress, drugs, bring on this reaction, antimalarial agents, sulfonamides, antibiotic, aspirin, nonsteroidal anti-inflammatory drugs, nsaids, nitrofurantoin, quinidine, quinine, exposure to certain chemicals, in mothballs, chronic spherocytic anemia is unaffected by exposure to these drugs, risk of acute hemolytic crisis, decreased by reviewing the family history, evidence of hemolytic anemias, spherocytosis, testing, giving any medications belonging, above class of chemicals, episodes, brief, newly produced, young, red blood cells have normal g6pd activity, risk factors, black, male, having a family history of g6pd deficiency, another type of this disorder, occur in whites of mediterranean descent, form is also associated, acute episodes of hemolysis, episodes, longer, severe than, in the the disorder, fatigue, paleness, shortness of breath, rapid heart rate, yellow skin color, jaundice, dark urine, enlarged spleen, severe hemolysis, hemoglobinuria, hemoglobin, in the urine, anemia, hemolysis, reduced g-6-pd activity, reticulocytosis following a hemolytic crisis, elevated bilirubin levels, elevated serum ldh, low serum haptoglobin, hemoglobin, in the urine, elevated absolute reticulocyte count, low red blood cell count, hemoglobin, heinz bodies present on examination, the peripheral blood smear using special stains, methylene blue test, methemoglobin reduction test, infection, drug, offending agent, the mediterranean form, in hemolytic crisis, require transfusions, spontaneous recovery from hemolytic crises, usual outcome, kidney failure, death, occur following a severe hemolytic event, symptoms of hemolytic anemia, due to g-6-pd deficiency develop, have g-6-pd deficiency, symptoms of hemolytic anemia, not disappear after treatment, g-6-pd must strictly avoid factors, precipitate an episode, drugs known to cause oxidative reactions, genetic counseling, genetic information of interest to heterozygous women, men.
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