histoplasmosis…

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lungs, acute histoplasmosis, disseminated histoplasmosis, histoplasmosis, disseminated in hiv patient, ohio river valley fever, histoplasmosis, fungal infection, histoplasma capsulatum, primarily affects the lungs but, spread to other organs, histoplasmosis, fungal infection, occur anywhere, in the world, united states, most common, in the southeastern, mid-atlantic, central states, lungs, the portal of entry, infection, histoplasma grows, a mold in soil, infection results from inhalation of airborne fungal particles, soil contaminated, bird, bat droppings, higher concentration of mold, histoplasmosis, have no symptoms, a short period of active infection, become chronic, spread throughout the body, most patients, symptomatic histoplasmosis, flu-like syndrome, pulmonary, lung, complaints related to underlying pneumonia, lung involvement, individuals, chronic lung disease, emphysema, bronchiectasis, at higher risk of a more severe infection, body responds to infection, extreme inflammation, irritation, swelling, presence of extra immune cells in affected area, up to 10% of patients, have complications involving the skin, bone/joints, lining, the heart, pericardium, small proportion of patients, histoplasmosis widespread, disseminated histoplasmosis, involve the blood, meninges, linings, the brain, adrenal glands, organs, very young, very old people, underlying immune disorders aids, at higher risk, disseminated histoplasmosis, symptoms depend on the underlying clinical syndrome, acute asymptomatic pulmonary, lung, histoplasmosis, no symptoms, acute symptomatic pulmonary histoplasmosis, fever, chills, cough, chest pain, breathing in, chronic pulmonary histoplasmosis, cough, shortness of breath, chest pain, excessive sweating, fever, resemble symptoms of pulmonary tuberculosis, coughing up blood, hemoptysis, disseminated histoplasmosis, fevers, headache, neck stiffness, skin lesions, mouth sores, histoplasma syndromes, joint pain, skin nodules, lumps, rashes, diagnosis of histoplasmosis depends on the underlying condition, analysis, the organism in sputum, lung tissue, blood, cerebrospinal fluid, csf, bone marrow tissue, antigen tests performed on blood, urine, csf, certain pathologic findings seen in tissue, support the diagnosis of histoplasmosis, mainstay of therapy, histoplasmosis is antifungal therapy, case of pulmonary histoplasmosis, oral agents itraconazole, ketoconazole, in disseminated disease, particularly meningitis, therapy, intravenous amphotericin is used followed by long-term suppression, an oral agent itraconazole, prognosis depends on the clinical syndrome, mortality is highest in disseminated histoplasmosis, up to 80%, decreased to 25%, inflammatory syndromes involving heart lining, pericarditis, joints, arthritis, skin nodules, rashes, erythema nodosum, erythema multiforme, fibrosing mediastinitis, scarring, in the chest, entrap structures, in the chest cavity, lymph nodes, heart, great vessels, esophagus, mediastinal granuloma, enlarged chest-cavity lymph nodes, compress structures esophagus, lung vessels, in individuals, weakened immune systems disseminated disease, involve the meninges, meningitis, side effects of medications, severe, amphotericin, complications of histoplasmosis, notify medical provider, live in an endemic area, histoplasmosis, develop flu-like symptoms, chest pain, cough, shortness of breath, many other illnesses, have similar symptoms, evaluated, the possibility of histoplasmosis, minimize exposure to dust in contaminated environments, chicken coops, bat caves, wear protective equipment masks, work in these environments.