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hypokalemic periodic paralysis
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periodic paralysis, hypokalemic, hypokalemic periodic paralysis, inherited disorder that causes, occasional episodes of muscle weakness, hypokalemic periodic paralysis, condition of intermittent episodes of muscle weakness, severe paralysis, one of a group of genetic disorders that includes hyperkalemic periodic paralysis, thyrotoxic periodic paralysis, disorder is distinguished from other forms of periodic paralysis in that people, disorder have normal thyroid function, very low blood levels of potassium, episodes of weakness, hypokalemic periodic paralysis, congenital, present from birth, inherited but occasionally occurs, a result of a non-inherited genetic mutation, the sperm, egg cell, inherited, an autosomal dominant disorder, one parent must transmit the gene, the baby to be affected, disorder involves attacks of muscle weakness, paralysis alternating, periods of normal muscle function, attacks, begin in adolescence, age 10, attacks of intermittent weakness that, not begin, adulthood, rare, disorders, frequency of attacks, from daily to yearly, episodes of muscle weakness, last between a few hours, one day, forms of periodic paralysis, last longer, an attack of muscle weakness, low level of potassium, in the bloodstream, serum potassium levels, normal between attacks, no decrease in total body potassium, potassium flows, bloodstream into muscle cells, attacks, insulin levels, affect the course, the disorder, people, insulin increases the flow of potassium into cells, weakness most commonly affects the muscles, the arms, legs, occasionally affect the eye muscles, muscles involved in breathing, swallowing, fatal, muscle strength is initially normal between attacks, repeated attacks, eventually cause worsening, permanent muscle weakness between attacks, attacks triggered by eating meals high in carbohydrate, salt, by consuming alcohol, attacks most commonly occur after sleep, rest, rare, exercise, rest after an exercise period, trigger an attack, risk is slightly higher in asian men who, thyroid disorders, thyrotoxic periodic paralysis, risks include having other family members, periodic paralysis, disorders that cause intermittent episodes of paralysis, primary effect, uncommon, hypokalemic periodic paralysis occurs in approximately 1 out of 100, 000 people, men, affected more often than women, have more severe symptoms, weakness, paralysis, most commonly located, shoulders, hips, involves, arms, legs, occurs intermittently, most commonly occurs on awakening, triggered by rest after exercise, triggered by heavy, high-carbohydrate, high-salt meals, alcohol consumption, lasts less than 24 hours, normal muscle strength between attacks, positive babinski's reflex, eyelid spasms between episodes, patient's thinking remains alert, attacks, suspect hypokalemic periodic paralysis symptoms come, potassium levels, attacks, disorders known to cause low potassium, not suspected, hypokalemic periodic paralysis is also likely, other family members have the disorder, between attacks, a physical examination shows nothing abnormal, an attack there leg stiffness, heaviness, in the legs, performing mild exercise, symptoms start, prevent a full blown attack, an attack, muscle reflexes decreased, absent, muscles go limp rather than staying stiff, muscle groups near the body, shoulders, hips, involved more often than the arms, legs, attempt to trigger an attack to aid in diagnosis by reducing potassium levels, administration of insulin, glucose, serum potassium is low, attacks but normal between attacks, confirming the diagnosis of hypokalemic periodic paralysis, an ecg, heart tracing abnormal, attacks, an emg, muscle tracing, normal between attacks, abnormal, attacks, a muscle biopsy, abnormalities, muscle weakness that involves, breathing, swallowing muscles, emergency situation, dangerous heart arrhythmias, attacks, goals of treatment, relief of acute symptoms, prevention of further attacks, potassium that is given, an attack, stop the attack, preferred that potassium be given by mouth, weakness is severe, intravenous potassium necessary, intravenous potassium, caution, in individuals, kidney disease, taking potassium, prevent attacks, a low-carbohydrate diet, avoidance of alcohol recommended, acetazolamide prevents attacks in many cases, possibly by reducing the flow of potassium, bloodstream, cells, potassium supplements necessary, acetazolamide, body to lose potassium, triamterene, spironolactone, prevent attacks in people who, not respond to acetazolamide, chronic attacks, eventually result in progressive muscle weakness that is present between attacks, hypokalemic periodic paralysis responds well to treatment, prevent, reverse, progressive muscle weakness, kidney stones, a side effect of acetazolamide, heart arrhythmias, attacks, difficulty breathing, speaking, swallowing, attacks, rare, progressive muscle weakness, have intermittent muscle weakness, family history of periodic paralysis, faint, have difficulty breathing, speaking, swallowing, emergency symptoms, hypokalemic periodic paralysis cannot be prevented, inherited, genetic counseling advised, couples at risk, the disorder, treatment of hypokalemic periodic paralysis prevents attacks of weakness.
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