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incontinentia pigmenti syndrome
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incontinentia pigmenti on the leg, incontinentia pigmenti on the leg, bloch-sulzberger's disease, incontinentia pigmenti syndrome, inherited disorder that causes, unusual blistering, the skin followed by increased pigmentation, incontinentia pigmenti syndrome, ips, inherited, a dominant x-linked trait, all cases, among females, condition lethal in males, ips, arise, a spontaneous mutation, infants, ips, born, blistery, vesicular, lesions which appear, streaks, lesions heal, rough bumps, eventually, these bumps clear but leave damaged, hyperpigmented, too much pigment, skin behind, after several years, skin returns to normal, adults, whorls, streaks of faint hypopigmentation, less pigment than normal, appear, ips, other problems, abnormal teeth, hair loss, central nervous system, cns, abnormalities, cns problems, retardation, delayed development, seizures, spasticity, paralysis, visual problems, develop, a third of affected people, blistering lesions, in the newborn, areas of hypopigmentation, whorls, unusual patterns of hyperpigmentation, abnormal teeth, delayed development, seizures, classic pigment changes, whorls, unusual patterns, lines of blisters, hair loss, retardation, spasticity, paralysis, abnormal retinal findings on eye examination, cataracts, strabismus, crossed eyes, microcephaly, abnormally small head, bone abnormalities, no one treatment, ips, therapies, aimed at specific problems, prognosis, depending on the degree of central nervous system involvement, visual impairment, secondary infections of blistered skin, mental retardation, delayed development, seizures, paralysis, muscle spasticity, difficulty walking, visual problems, family history of this disorder, considering having children, child shows symptoms that characterize this disorder, genetic counseling helpful, a family history of ips who want to have children.
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