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medullary cystic kidney disease
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kidney anatomy, kidney cyst, gallstones, ct scan, kidney, blood, urine flow, familial juvenile nephrophthisis, senior-loken syndrome, medullary cystic disease, hereditary disorder, kidneys gradually lose ability to function, cysts, in the medulla, center, each kidney, medullary cystic kidney disease, mckd, very similar, childhood disease juvenile nephronopthesis, nph, lead to scarring, the kidney, formation of fluid-filled cavities, in the deeper parts, the kidney, medullary cysts, nph occurs in young children, due to autosomal recessive inheritance, mckd occurs in older patients, transmitted in an autosomal dominant pattern, in these conditions, kidneys don't concentrate the urine enough, excessive urine production, loss of sodium, salt supplementation required, additional kidney problems follow, most mckd patients reach end-stage kidney disease between the ages of 30, nph patients, 4 years of age, it begins, nph associated, non-kidney features, abnormalities, in the eyes, mckd is limited, kidneys only, in the course, need to urinate at night, nocturia, excessive urination, polyuria, weakness, low blood pressure, excessive salt intake, in the disease, symptoms of kidney failure, pale skin, weakness, unintentional weight loss, nausea, vomiting, general ill feeling, fatigue, headache, frequent hiccups, generalized itching, easy bruising, bleeding, vomiting blood, blood, in the stool, decreased alertness, drowsiness, lethargy, confusion, delirium, coma, muscle twitching, muscle cramps, seizures, increased skin pigmentation, skin, appear yellow, brown, reduced sensation, in the hands, feet, areas, in the course, physician, identify, patient is passing large amounts of diluted urine, salt wasting, urine specific gravity is low, fixed, blood pressure low, require salt supplements, diagnosis, established, abdominal ultrasound, abdominal ct scan, small kidneys, multiple cysts on the kidneys, renal biopsy, tubulo-interstitial nephropathy, medullary cysts, the disease progresses, kidney failure follows, increasing creatinine levels, increasing bun, blood urea nitrogen, decreasing creatinine clearance, elevated blood pressure, anemia, shown on complete blood count, shrunken kidneys, shown on ultrasound, no cure, treatment focuses on controlling symptoms, minimizing complications, slowing the progression, the loss of water, salt, need a liberal intake of both to avoid dehydration, the disease progresses, kidney failure develops, appropriate changes, high blood pressure develops, anti-hypertensive medications needed, anemia, require erythopoeitin treatment to build red blood cells, diet, modified to limit phosphorous-, potassium-containing foods, once end-stage kidney disease approaches, dialysis started, a suitable donor becomes available, a kidney transplant performed, no cure, chronic kidney failure resulting from medullary cystic disease, untreated, progresses to end-stage kidney disease, lifelong treatment, control the symptoms of chronic kidney failure, hyponatremia, a disorder of fluid, electrolyte imbalance, end-stage kidney disease, pericarditis, cardiac tamponade, platelet dysfunction, gastrointestinal bleeding, ulcers, hemorrhage, anemia, peripheral neuropathy, weakening, the bones, fractures, joint disorders, permanent skin pigmentation changes, itching, changes in glucose metabolism, changes in electrolyte levels, electrolyte abnormalities, hyperkalemia, miscarriage, menstrual irregularities, infertility, congestive heart failure, hypertension, have any symptoms of medullary cystic disease, an inherited disorder, the way it is inherited, prevention, not be possible.
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