mosaicism…

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chromosomal mosaicism, gonadal mosaicism, mosaicism, a condition where an individual has two, cell populations that differ in genetic makeup, situation, affect any type of cell, blood cells, gametes, egg, sperm cells, skin, mosaicism detected, chromosome evaluation, described, a percentage, the cells examined, normal chromosome finding in males is 46 xy, normal in females is 46 xx, examples of chromosomal mosaicism, turner syndrome mosaic, a female, a certain percentage, the normal cell line, 46, xx, plus another percentage of an abnormal cell line associated, turner syndrome, x, klinefelter syndrome mosaic, a male, a percentage, the normal cell line, 46, xy, plus another percentage of an abnormal cell line associated, klineflter syndrome, 47, xxy, down syndrome mosaic, a male, the normal cell line, 46, xy, plus an abnormal cell line, 47, xy, +21, a female, the normal cell line, 46, xx, plus an abnormal cell line, 47, xx, +21, in down syndrome, individual has an extra chromosome no, mosaicism occurs, a result of an error in cell division very early in fetal development, from person to person, very difficult to predict, normal cells, abnormal cells, associated abnormalities, not be, severe, likely need to be repeated, confirmation, to help further define the type, severity, the genetic mosaicism, depend on the specific type of genetic disease, patients, mosaicism, require less intense treatment than those, the typical form, 100% of cells affected, they more mildly affected, of cells, abnormal, outlook depends greatly on the degree of mosaicism, difficult to predict the effects of having two different cell lines in one person, patients, a high percentage of abnormal cells share the same prognosis, the typical form of that particular disease, having 100% abnormal cells, patients, a low percentage of abnormal cells quite mildly affected, in fact, discover that they have mosaicism after giving birth to a child who has the typical, non-mosaic, form of disease, complications, signs, the type, percentage of cells, the genetic change, finding of mosaicism, cause confusion, uncertainty, a referral to a genetics professional, help assess the specific circumstances, provide recommendations, further testing, currently no known prevention, mosaicism.