pneumocystis carinii pneumonia…

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lungs, aids, pneumocystosis, pneumocystosis, pcp, pneumocystis jiroveci, an infection, the lungs, fungus pneumocystis carinii, pcp, pneumonia, fungal organism pneumocystis carinii, is widespread, in the environment, not a pathogen, does not cause illness, in healthy individuals, in individuals, weakened immune systems, due to cancer, hiv/aids, solid organ, bone marrow transplantation, individuals receiving chronic corticosteroids, medications that affect the immune system, pneumocystis carinii, lead to a lung infection, individuals, advanced aids, particular interest, pcp was a relatively rare infection, aids epidemic, the use of preventive antibiotics, pcp, up to 70% of individuals, advanced aids would develop pcp, pcp, in the setting of aids, develops slowly, less severe, several weeks of cough, fevers, progressive shortness of breath, exertion, individuals, pcp who, not have aids, get sick faster, more acutely ill, fever, cough, dry, shortness of breath, exertion, rapid breathing, x-ray, the chest, reveal abnormal lung findings, yet up to 10% of individuals, pcp, in the setting of aids, normal chest x-ray, sputum induction, special stains to detect pneumocystis carinii, bronchoscopy, lavage, sputum induction is negative, lung biopsy, rarely be needed, above studies fail to yield a diagnosis, blood gases, decreased oxygen level in blood, helps in determining whether an individual might benefit from corticosteroids, mainstay of treatment, pcp is antimicrobial therapy, trimethoprim-sulfamethoxazole, drug of choice, pcp, given orally, via the intravenous route depending on the severity, the illness, in individuals, low levels of oxygenation, moderate to severe pcp, corticosteroids, frequently used, antimicrobials used, the treatment of pcp, pentamidine, trimethoprim-dapsone, clindamycin, primaquine, atovaquone, pneumocystis carinii pneumonia, life-threatening, death, due to respiratory failure, hence early, effective treatment, moderate to severe pcp in individuals, aids, use of adjunctive corticosteroids has also led to decreased mortality, respiratory failure, require mechanical ventilation, pneumothorax, pleural effusion, extremely rare, individuals, weakened immune systems, due to aids, cancer, transplantation, corticosteroid use should notify physician, they develop cough, fevers, shortness of breath, many infections, lead to similar symptoms, a medical evaluation must be performed to rule out opportunistic infections, pcp, preventive therapy, aids patients, individuals on chronic high dose corticosteroids, individuals, previous episodes of pcp, most effective preventive drug is trimethoprim-sulfamethoxazole, options include dapsone, atovaquone, pentamidine.