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primary hyperparathyroidism
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endocrine glands, parathyroid glands, parathyroid-related hypercalcemia, primary hyperparathyroidism involves, excessive production of parathyroid hormone, enlargement of one, the parathyroid glands, parathyroid glands, the neck, 4 corners, the thyroid gland, glands produce parathyroid hormone, pth, regulates calcium, phosphorus balance, in primary hyperparathyroidism, increased secretion of parathyroid hormone occurs, one, the glands have, become enlarged, effects of increased calcium, seen in several body systems, the skeletal, gastrointestinal, renal, kidney, muscular, central nervous system, common in people over 60, seen in younger adults, women, more likely to be affected than men, radiation, head, neck increases risk, hyperparathyroidism in childhood is distinctly unusual, disease, parathyroid carcinoma, fatigue, fractures, decreased height, upper abdominal pain, loss of appetite, nausea, muscular weakness, muscle pain, depression, personality changes, stupor, possibly coma, kidney stones, increased urination, radioimmunoassay of parathyroid hormone shows an increased level, serum calcium is increased, serum phosphorus decreased, serum alkaline phosphatase increased, bone x-ray, bone reabsorption, fractures, imaging, the kidneys, ureters, calcification, obstruction, ecg, abnormalities, tests, calcium, urine, calcium, ionized, bone density, markers of bone resorption, n-telopeptide, pyridinoline, deoxypryridinoline, treatment depends upon the severity, mild hypercalcemia monitored, rather than treated, impaired renal function, kidney stones, bone demineralization occur, encouraging fluids given by mouth, prevent kidney stone formation, avoiding sedentary lifestyle, immobilization, avoiding thiazide-type diuretics, using estrogen therapy, postmenopausal women, symptomatic, severe hypercalcemia, hospitalization required, rehydration using intravenous fluids started, medications to quickly bring down the calcium given, bisphosphonates, calcitonin, surgical removal of a tumor, excess parathyroid tissue from hyperplasia is indicated, hypercalcemia is more severe, complications, kidney stones, nephrolithiasis, pancreatitis, psychiatric disease, bone demineralization, surgery is also recommended, younger patients, less than 50 years old, prognosis is good, mild cases, in the majority, complications that result from excess calcium deposits, skeletal damage, urinary tract infection, due to kidney stones, obstruction, pancreatitis, pseudogout, symptoms indicate that primary hyperparathyroidism present, signs of complications develop.
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