proximal renal tubular acidosis…

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kidney anatomy, kidney, blood, urine flow, renal tubular acidosis, proximal, type ii rta, rta, proximal, renal tubular acidosis type ii, term "renal" refers, kidney, kidney contains over a million functional units, nephrons, filter blood, produce urine, a blood buffer, bicarbonate is reabsorbed, blood, in the proximal tubule of each nephron, not reabsorbed properly, body is left an acidic state, acidosis, healthy, body is very slightly alkaline, acidic substances, carbon dioxide, buffered, counteracted, by alkaline substances, primarily bicarbonate, kidneys regulate body's ph by controlling acids, bicarbonate buffer, an acidic state in body, high carbon dioxide levels, respiratory acidosis, low bicarbonate levels, metabolic acidosis, proximal renal tubular acidosis, type ii rta, from poor bicarbonate reabsorption by the proximal tubules, leads to lower bicarbonate buffer, in the blood, causing metabolic acidosis, type ii rta is less common than classical type i rta, most commonly occurs, infancy, spontaneously resolve, many different molecular abnormalities, lead to type ii rta, occur in an isolated form, general problems, the proximal tubule, fanconi's syndrome, type ii rta tend to reabsorb chloride to compensate, have high blood serum chloride levels, low in potassium, fatigue, weakness, confusion, decreased alertness, increased rate of breathing, muscle pain, breathing rate rapid, body attempts to decrease carbon dioxide, have symptoms of osteomalacia, rickets, dehydrated from loss of water, urine, low potassium levels interfere, the kidney's ability to concentrete the urine, measurements, the blood ph, urine ph, a problem, urine alkaline, change, the body becomes more acidic, a urinalysis, abnormal levels of phosphate, calcium, glucose, amino acids, in the urine, arterial blood gases, blood chemistries, indicate metabolic acidosis, electrolyte abnormalities, tests, urine potassium level, blood potassium level, urine citric acid, urine calcium, acid loading test, ph, goal, restore the normal ph, acid-base level, a normal electrolyte balance, indirectly correct bone disorders, reduce the risk of osteomalacia, osteopenia in adults, adults, need no treatment, all children need alkaline medication, prevent bone disease, rickets in particular, to permit normal growth, underlying cause, alkaline medications include sodium bicarbonate, potassium citrate, correct the acidic condition, correct low potassium levels, thiazide diuretics, indirectly decrease bicarbonate loss but, exacerbate the low potassium levels, vitamin d, calcium supplements needed to aid, in the reduction of skeletal deformities resulting from osteomalacia, rickets, the cause of proximal renal tubular acidosis, resolve spontaneously, effects, complications, permanent, life-threatening, treatment, successful, osteomalacia, rickets, electrolyte disturbances, hypokalemia, have symptoms of proximal renal tubular acidosis, new symptoms develop, pain, in the bones, flank, abdomen, skeletal deformities, increased heart rate, irregular heartbeat, muscle cramps, decreased urine output, bloody urine, get medical help immediately, decreased alertness, orientation, decreased consciousness, seizures develop, the disorders that cause proximal renal tubular acidosis, not preventable.