secondary systemic amyloid…

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amyloidosis on the fingers, amyloidosis on the face, antibodies, secondary systemic amyloid, insoluble protein fibers, become deposited in tissues, organs impairing function, found in association, chronic infection, chronic inflammatory disease, exact mechanism that causes, secondary systemic amyloid, risk factors include chronic inflammatory, infectious diseases, secondary systemic amyloid occurs in association, multiple myeloma, chronic conditions, that last, rheumatoid arthritis, tuberculosis, long term paraplegia, bronchiectasis, cystic fibrosis, chronic osteomyelitis, recurrent pyogenic, involving pus, skin infection, abscess, decubitus ulcers, chronic renal dialysis, juvenile chronic arthritis, systemic lupus erythematosus, reiter's syndrome, ankylosing spondylitis, hodgkin's disease, sjogren's syndrome, hairy cell leukemia, in primary amyloidosis, organs that, become affected, the deposits, organs exhibit reduced function, fatigue, numbness of hands, feet, weak hand grip, weight loss, shortness of breath, swelling, the extremities, swallowing difficulties, irregular heart rhythm, bleeding, in the skin, enlarged tongue, specific organ damage is suspected, testing to confirm amyloidosis of that organ, a biopsy of an affected tissue, organ that is positive, amyloid, tests, a skin biopsy of subcutaneous fat, a rectal mucosa biopsy, a bone marrow biopsy, all of these tests, convenient, safe, likely to be positive, confirmation, physical examination, abdominal ultrasound shows an enlarged liver, spleen, cardiac evaluation reveals arrhythmias, abnormal heart sounds, signs of heart failure, ecg shows abnormalities, echocardiogram shows poor wall motion, stiff heart muscle, cardiomyopathy, renal evaluation reveals renal failure, nephrotic syndrome (excessive protein, in the urine, urinalysis that shows protein, casts, fat bodies, increased serum creatinine, increased bun, an evaluation, carpal tunnel syndrome, nerve conduction velocity that shows conduction block, weak hand grip associated, weakness, the thumb, treatment, the underlying condition, prevent progression, the amyloidosis, no specific treatment, amyloid, severity, the disease depends upon the organs, heart, kidney involvement, lead to organ failure, death, systemic involvement is leads to death, 1, 3 years, heart failure, kidney failure, endocrine failure, respiratory failure, experience symptoms of this condition, numbness, weak grip, shortness of breath, swelling, bleeding, irregular heart rhythm, serious symptoms that, require prompt intervention, no known primary prevention, secondary prevention includes aggressive treatment, control of diseases known to predispose, development of amyloid.