smallpox…

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smallpox lesions, variola, major, minor, variola, smallpox, viral disease characterized by a skin rash, a high death rate, smallpox was once found throughout the world, causing illness, death wherever it occurred, smallpox was primarily a disease of children, young adults, family members often infecting each other, a massive program by the world health organization, eradicated all known smallpox viruses, world in 1977, except, samples that were saved by various governments, research purposes, vaccine was discontinued, in the united states in 1972, in 1980, who recommended that all countries stop vaccinating, smallpox, in 1980, who also recommended that the remaining virus samples be transferred to two who laboratories, storage, laboratories were the centers, disease control, cdc, in atlanta, georgia, a laboratory in russia, russia, started a program to produce the smallpox virus in mass quantities, specifically, bombs, weaponry, believe that other countries iraq, iran, north korea, hold some stores, the smallpox virus, researchers continue to debate whether, not to kill the last remaining samples, the virus, to preserve it in case there some future reason to study it, according, cdc, the vaccine has not been administered, 1972, persons who had received the vaccine, likely susceptible now, never been vaccinated, not known how long previous vaccinations would remain effective, unlikely that people would still have a high enough level of immunity to protect against the virus, risk factors, smallpox, laboratory worker who handles the virus, rare, environment, virus was released, a biological weapon, risk of terrorism, conceivable that smallpox could be deliberately reintroduced, population, smallpox could be released by aerosol, would spread, the virus remains very stable in aerosol form, would take no more than 50-100 cases to cause legitimate concern on an international level, emergency measures would need to be taken, smallpox is highly contagious, one person to another, most contagious, first week, spread, saliva droplets, continue to be contagious, scabs, rash fall off, spread, bed sheets, clothing, researchers believe that the smallpox infection, released in aerosol form, under favorable conditions, sunlight, could remain viable, in unfavorable conditions, virus, remain viable, 6 hours, clear evidence that shows that the virus, remain viable on bed linens, clothes, significant periods of time, smallpox has two forms, variola major, serious illness, a mortality rate according, cdc of 30%, in unvaccinated people, variola minor, a milder infection, a mortality rate of less than 1%, incubation period, smallpox is approximately 12-14 days, high fever, fatigue, severe headache, backache, malaise, rash, raised, pink on the skin, starting centrally, spreading outwards, first the mucosa, the mouth, throat, face, forearms, trunk, legs, rash turns to pus-filled lesions that, become crusty on the eighth, ninth day, delirium, vomiting, diarrhea, excessive bleeding, virus, seen by electron microscope, by culture, low white blood cell count initially, increases later, in the disease, low platelet count, dic panel, positive in cases of hemorrhage, antibodies turn positive soon, infection is complete, smallpox vaccination is given, 1-4 days of exposure, prevent illness, at least lessen the degree of illness associated, once the disease symptoms have started, limited, no agent, specifically made, treating smallpox, antibiotics, secondary infections, vaccinia immune globulin, antibodies against a disease similar to smallpox, help shorten the disease, a diagnosis of smallpox were made, exposed persons would need to be isolated, isolation would include not just the person who contracted the disease, all other face-to-face contacts, individuals would need the vaccine, monitored, emergency measures to protect a broader segment, the population would have to be implemented, the recommended guidelines, cdc, federal, local health agencies, was a major illness, significant mortality, 30%, bacterial infections, skin, sites, the lesions, pitted scars from pustules, arthritis, bone infections, pneumonia, severe bleeding, eye infections, brain inflammation, encephalitis, death, think you, have been exposed to smallpox, contact health care provider, smallpox has been eradicated, would be very unlikely, have worked, the virus, has been an act of bioterrorism, were vaccinated, smallpox, but the vaccination is no longer given, the virus has been eradicated, according, cdc, united states has supply, the smallpox vaccine sufficient, the entire population at this time, complications associated, the vaccine, should the vaccine need to be given, in the future to control an outbreak, treated rashes, potential complications, more serious, risk of complications is relatively low, chance of encephalitis, could be a fatal complication, 1 out of 300,000, smallpox was eradicated, general population was no longer vaccinated, the potential complications, costs began to outweigh the benefits of taking it, experience of vaccination of both military personnel, civilian health care workers in 2002-2003 suggested that the risk was very low but nonetheless present, very small numbers of people had unforeseen reactions, smallpox vaccination is not currently done, members, the general public, of mid-2003, further vaccination outside of military personnel is likely to be done, closely supervised fashion, in health care workers, emergency responders, ongoing review of smallpox vaccination, the current, newer vaccines.