systemic sclerosis, scleroderma…

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raynaud's phenomenon, crest syndrome, sclerodactyly, telangiectasia, crest syndrome, progressive systemic sclerosis, scleroderma, scleroderma, diffuse connective tissue disease characterized by changes, in the skin, blood vessels, skeletal muscles, internal organs, scleroderma, produce local, systemic symptoms, course, severity, widely in those affected, excess collagen deposits, in the skin, organs produce the symptoms, damage to small blood vessels, the skin, organs also occurs, skin, ulceration, calcification, changes in pigmentation, systemic features, fibrosis, degeneration, the heart, lungs, kidneys, gastrointestinal tract, affects people 30 to 50 years old, women, affected more often than men, risk factors, occupational exposure to silica dust, polyvinyl chloride, blanching, blueness, redness of fingers, toes in response to heat, cold, raynaud's phenomenon, pain, stiffness, swelling of fingers, joints, skin thickening, shiny hands, forearm, skin is hard, tight, mask-like facial skin, ulcerations on fingertips, toes, esophageal reflux, heartburn, difficulty swallowing, bloating after meals, weight loss, diarrhea, constipation, shortness of breath, additional symptoms that associated, wrist pain, wheezing, skin, abnormally dark, light, joint pain, hair loss, eye burning, itching, discharge, examination, the skin, tightness, thickening, hardening, esr is elevated, rheumatoid factor, elevated, an antinuclear antibody test, positive, urinalysis, protein, microscopic blood, a chest x-ray, fibrosis, pulmonary function studies often show restrictive lung disease, a skin biopsy, treatment involves medication, aspirin, nonsteriodal anti-inflammatory drugs, nsaids, corticosteroids, to treat symptoms of inflammation, pain, treatments, directed at specific manifestations of systemic sclerosis, antacids, intestinal motility drugs, heartburn, related symptoms, medications that increase blood flow, raynaud's phenomenon, blood pressure medications, particularly ace inhibitors, high blood pressure, kidney problems, includes a combination, of physical therapy, skin, joint protection techniques, avoiding cold, in the case of raynaud's phenomenon, see scleroderma, support group, majority of those affected, disease is progressive, remission occurs, a slow progression, people who only have skin involvement have a better prognosis, probable outcome, death, occur from gastrointestinal, cardiac, kidney, pulmonary, lung, involvement, cardiac failure, renal failure, pulmonary fibrosis, malabsorption, inadequate absorption of nutrients, intestinal tract, symptoms of this disorder, have scleroderma, become worse, new symptoms develop, no known prevention, minimize exposure to silica dust, polyvinyl chloride.