thrombolytic therapy, tissue plasminogen activator, tpa…

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stroke, thrombus, tpa, alteplase, reteplase, tenecteplase, activase thrombolytic agent, clot-dissolving agents, reperfusion therapy, thrombolytic therapy, drug that break ups, dissolves blood clots, the main cause of both heart attacks, stroke, 1996, tpa has been approved by the food, drug administration, fda, the treatment of stroke, heart attack, according, american heart association, aha, tpa is given, the first 3 hours of a stroke, reduce permanent disability, 12 hours, the onset of a heart attack, person has a better chance, survival, recovery, various drugs that dissolve clots, tpa is currently used most often, others include streptokinase, sk, reteplase, tenecteplase, urokinase, lanoteplase, staphylokinase, heart attack, according, american college of cardiology, acc, each year 800,000 persons, in the united states have acute heart attacks, 213,000 die, who die from heart attacks generally die, 1 hour, initial onset of symptoms, they get, hospital, guidelines, someone, good candidate, using tpa, many national groups, working together to decrease the time it takes to get people having a heart attack to facilities where tpa, sooner thrombolytic therapy is given, better the outcome, window of opportunity, very short amount, person having an acute heart attack, tpa works by dissolving a major clot quickly, clot, likely blocking one, the coronary arteries that, allows blood, oxygen get, heart muscle, by dissolving the clot, blood is able to start flowing again to that area, the heart, blood flow, heart is started again rapidly, prevent long-term damage, heart muscle, stop an event that could have been fatal, drug is successful in restoring some blood flow, heart muscle in approximately 75% of patients, the resultant blood flow, not be entirely normal, further therapy, cardiac catheterization, physicians base decisions, to give tpa, heart attack on many factors, a history of chest pain, results of an ecg test, factors used, someone, good candidate, tpa include age, medical history, gender, history of previous heart attack, history of diabetes, history of low blood pressure, increased heart rate, person is elderly, older than 70 years, generally, tpa, not be given person has had a recent head injury, trauma, surgery, bleeding problems, uncontrolled high blood pressure, bleeding ulcers, pregnancy, stroke, close to 80% of all strokes, ischemic strokes, caused, blood clots form in one place, travel to a smaller blood vessel, in the brain, blocking the blood flow to that area, strokes of this nature, tpa, dissolve the clot quickly, tpa, limit the amount, permanent disability, ischemic stroke, 3 hours, the initial symptoms, the stroke, decision to administer the drug, based upon the history, physical exam consistent, a significant stroke, a brain ct scan to exclude bleeding, someone is having a hemorrhagic stroke, a stroke, bleeding, in the brain, tpa is not given, this could worsen the stroke by causing increased bleeding, ischemic strokes often occur, a person is at rest, not under physical duress, hemorrhagic strokes often occur, sort of physical exertion, diagnosis, the actual type of stroke difficult, risk of bleeding from tpa, concern, generally, benefits of receiving it outweigh the risks, timely manner, hemorrhage, bleeding, most common risk associated, the administration of tpa therapy, bleeding which is mostly minor, gum, nose bleeding, occur in approximately 25% of people, bleeding, brain occurs approximately 1%, the time, true, stroke, heart attack patients, key, people suffering, a heart attack, a stroke is recognizing that both conditions, medical emergencies, sooner transportation, tpa takes place, acceptable candidates, better the chance that person has, good outcome, refer, stroke, heart attack articles, specific symptoms, conditions, suspect you, someone is suffering from symptoms of a heart attack, stroke, should seek help immediately!.