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toxoplasmosis
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slit-lamp exam, congenital toxoplasmosis, antibodies,
toxoplasmosis, infection, the protozoan intracellular parasite toxoplasma gondii, toxoplasmosis is found in humans worldwide, in many species of animals, birds, cats, the definitive host, the parasite, human infection results from ingestion of contaminated soil, careless handling of cat litter, ingestion of raw, undercooked meat, lamb, pork, beef, transmission, a mother to a fetus, the placenta, congenital infection, by blood transfusion, solid organ transplantation, over 80-90% of primary infections produce no symptoms, incubation period, symptoms is 1 to 2 weeks, congenital toxoplasmosis, infection, toxoplasma gondii, pregnant woman, up to 50% of such infections transmitted, fetus, signs of congenital infection present at birth, develop over the first few months of life, infants, signs of central nervous system disorders, enlargement, the liver, spleen, blindness, mental retardation, toxoplasmosis also affects people who, immunosuppressed, a result of aids, cancer, immunosuppressive therapies, affect the brain, lung, heart, eyes, liver, in non-immunosuppressed people, mild febrile illness resembling mononucleosis, enlarged lymph nodes, in the head, neck, headache, sore throat, muscle pain, in congenital infection, central nervous system disorders, enlarged liver, spleen, rash, fever, jaundice, anemia, inflammation, the retina, the eye, psychomotor, learning disorders, not appear, later, in an immunosuppressed person, brain lesions, fever, headache, confusion, seizures, abnormal neurological findings, retinal inflammation causing blurred vision, infection, presence of cysts, serologic titers, toxoplasmosis, mri of head, cranial ct scan, brain biopsy, slit lamp examination reveals characteristic retinal lesions, no treatment, except children, prevent retinal inflammation, treatment of women in pregnancy is controversial, the toxicity, the medications, treatment is still advocated, medications to treat the infection, pyrimethamine, sulfonamide drugs, folinic acid, clindamycin, trimethoprim-sulfamethoxazole, treatment in aids patients is continued, the immune system is weak, prevent reactivation, acute infection in children, retinochoroiditis, inflammation, the retina, toxoplasmosis in adults has a good prognosis, probable outcome, immune system is healthy, chronic infection, symptoms, benign, harmless, spread, the infection in immunocompromised hosts, fatal, permanent disability in infants, blindness, learning disorders, recurrence, symptoms of toxoplasmosis occur, urgent, emergency conditions exist disorder occurs in an immunosuppressed person, baby, confusion, seizures, severe symptoms develop, avoid undercooked meats, freeze meat to -20 degrees celsius, 2 days, protect children's play areas from cat, dog feces, wash the hands thoroughly after contact, soil that contaminated, animal feces, pregnant women should have blood examined, toxoplasma antibody, negative results should take measures, prevent infection by avoiding exposure to cat feces, not cleaning litter boxes, cooking meat thoroughly, washing hands thoroughly after handling raw meat, patients, hiv disease should have toxoplasma antibody titers checked, the blood test, positive, cd4 count is less than 200, patients, given prophylactic antibiotics, trimethoprim-sulfamethoxazole, medication of choice.
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