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von willebrand's disease…

 

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blood clot formation, blood clots, von willebrand's disease, hereditary bleeding disorder, a deficiency of von willebrand factor, von willebrand factor helps platelets to stick, blood vessel wall, to each other, is necessary, normal blood clotting, von willebrand's disease, most common hereditary bleeding disorder, affects both sexes approximately equally, most cases, bleeding, occur after a surgical procedure, tooth extraction, condition is worsened by the use of aspirin, nonsteroidal anti-inflammatory drugs, nsaids, bleeding, decrease, pregnancy, disease is very common, affecting at least 1%, the population, a family history of a bleeding disorder, primary risk factor, in women, heavy, prolonged menstrual bleeding, von willebrand's is more common in caucasian women than african american women, nose bleeds, bleeding, the gums, abnormal menstrual bleeding, bruising, skin rash, normal platelet count, prolonged bleeding time, reduced von willebrand factor level, reduced platelet aggregation, platelet aggregation test, ristocetin co-factor is reduced, tests, factor viii level, von willebrand factor multimers, most patients, bleeding is mild under most circumstances, trauma occurs, surgery is scheduled, cryoprecipitate, ddavp, given to raise the levels of von willebrand factor, decrease the tendency toward bleeding, fresh plasma, certain factor viii preparations, decrease bleeding, subtypes of von willebrand disease, not respond to ddavp, subtype, determined, prior to reliance on ddavp, significant bleeding challenge, a trial of ddavp, prior to surgery to test whether von willebrand factor levels increase, patients, disorder should not take nonsteroidal anti-inflammatory drugs, nsaids, aspirin, ibuprofen, consulting health care provider, women, condition generally, not experience, excessive bleeding, childbirth, life span, normal, this disease is genetically transmitted, genetic counseling recommended, parents, post-operative hemorrhage, bleeding, bleeding occurs, no reason, scheduled, surgery, in an accident, sure to notify the health care providers, condition.



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