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wegener's granulomatosis
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adenocarcinoma, chest x-ray, wegener's granulomatosis on the leg, respiratory system, midline granulomatosis, wegener's granulomatosis, rare disorder that causes blood vessels, in the upper respiratory tract, nose, sinuses, ears, lungs, kidneys to, become swollen, inflammed, eyes, skin, joints may also be affected, arthritis occurs in about half of all cases, wegener's granulomatosis is thought to be an autoimmune disorder, patients, disease develop sores, lesions, in the respiratory tract, kidneys, kidney lesions cause glomerulonephritis, which may result in blood, in the urine, kidney failure, kidney disease, quickly get worse, untreated, kidney failure, death occur in more than 90% of patients, wegener's granulomatosis, common in middle-aged adults, men, affected twice, women, rare in children, has been seen in infants, young, 3 months old, frequent sinusitis, most common symptom, early symptoms include persistent fever, an obvious cause, night sweats, fatigue, and malaise, an ill feeling, chronic ear infections may also come before the diagnosis of wegener's granulomatosis, upper respiratory symptoms include nose bleeds, pain, sores around the opening, the nose, loss of appetite, weight loss, common, skin lesions typically occur, no one typical lesion associated, symptoms of kidney disease present, not always, urine bloody, first appears, red, smoky urine, eye problems develop, significant number of patients, they may range from mild conjunctivitis to severe swelling, the eye, weakness, cough, or coughing up blood, bloody sputum, shortness of breath, wheezing, chest pain, rashes, joint pains, a variety of tests performed, biopsy of abnormal tissue, open lung biopsy, upper airway biopsy, nasal mucosal biopsy, bronchoscopy, transtracheal biopsy, kidney biopsy, urinalysis to look, signs of kidney disease protein, blood, in the urine, presence of kidney disease is necessary to make a definitive diagnosis of wegener's granulomatosis, chest x-ray, bone marrow aspiration, blood tests to look, antibodies that the body makes against its own tissue, corticosteroids, cyclophosphamide, methotrexate, azathioprine produces long-term remission in over 90% of patients,
support groups, others who suffer from similar diseases, help patients, families learn, adjust, changes associated, the treatment, most people recover, develop chronic renal failure, patients, die, a few months, complications, result from lack of treatment, chronic kidney failure, hemoptysis, coughing up blood, respiratory failure, inflammation, the eyes, nasal septum perforation, hole inside the nose, rash, medications, treat the disease, cause side effects, lead to complications, chest pain, coughing up blood, blood, in the urine, symptoms of this disorder, no preventive measures,
murray j, nadel j, textbook of respiratory medicine, 3rd ed, philadelphia, pa, w, b, saunders company, 1462-1463.
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