yaws…

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antibodies, frambesia tropica, yaws, chronic infection, bacteria treponema pallidum, subspecies pertenue, primarily affects the skin, bones, joints, yaws, infection, spiral-shaped bacterium, spirochete, treponema pertenue, closely related, organism that causes, syphilis, disease is not sexually transmitted, yaws mainly affects children in rural, warm, tropical areas, primarily caribbean islands, latin america, west africa, india, southeast asia, yaws is transmitted by direct contact, skin lesions of infected people, two to four weeks after infection, child develops a sore "mother yaw", organism entered the skin, sore appears, a "raspberry-like" growth, group of papules, site of infection, painless, lesions, persist, additional satellite lesions, appear shortly, mother yaw heals, children, develop inflammation, the bones, fingers, final stage involves destructive lesions, the skin, bones, lead to severe disfigurement, disability, occurs, 20% of untreated individuals, initial, single skin lesion, grow slowly, raspberry-like appearance, form an ulcer, painless, satellite lesions, become large nodules/growths throughout the body, have superficial erosions in secondary yaws, fever present in secondary yaws, bone pain/bone destruction, saber shins, finger inflammation, dactylitis, diagnosis, confirmed, examining a sample, a skin lesion under a special type of microscope, darkfield examination, no specific blood test, yaws, closely related, bacterium that causes, syphilis, blood tests, syphilis positive in yaws, mainstay of treatment, single dose of penicillin g, relapse is rare, appropriately treated in its early stages, yaws is highly curable, skin lesions, take several months to heal, treated in its late stage, significant disfigurement, already be present, not be fully reversible, yaws, disfiguring, disabling, it, gross destruction, the skin, bones, cause deformities, the legs, nose, palate, upper jaw, contact medical provider, child have a chronic skin, bone lesion, have resided in tropical areas where yaws is known to occur, mass campaigns, eradication of yaws via penicillin treatment, in the 1950s, 1960s have dramatically decreased the worldwide incidence of yaws.