zollinger-ellison syndrome…

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endocrine glands, z-e syndrome, gastrinoma, zollinger-ellison syndrome, abnormal production, the hormone gastrin, a small tumor, gastinoma, pancreas produces the high levels of gastrin, in the blood, zollinger-ellison syndrome, tumors, found, in the head, the pancreas, upper small bowel, tumors produce the hormone gastrin, gastrinomas, high levels of gastrin cause overproduction of stomach acid, high stomach acid levels lead to multiple ulcers, in the stomach, small bowel, patients, zollinger-ellison syndrome, experience abdominal pain, diarrhea, diagnosis is also suspected in patients, severe ulceration, the stomach, small bowel, gastrinomas occur, single tumors, multiple tumors, one-half to two-thirds of single gastrinomas, malignant tumors that commonly spread, liver, nearby lymph nodes, nearly 25% of patients, gastrinomas have multiple tumors, multiple endocrine neoplasia type i, men i, men i patients often have tumors, the pituitary gland, brain, parathyroid, neck, glands, tumors, the pancreas, pain, vomiting blood, occasional, diarrhea, gastrin level is increased, a secretin stimulation test is positive, a calcium infusion test is positive, an abdominal ct scan shows a tumor, tumors, pancreas, early small bowel, an octreotide scan shows a tumor, in the pancreas, early small bowel, exploratory surgery shows the location of a tumor, a class of acid-suppressing medications, proton pump inhibitors, omeprazole, lansoprazole, first line treatment of zollinger-ellison syndrome, drugs dramatically reduce acid production by the stomach, promote healing of ulcers, in the stomach, small bowel, provide relief of abdominal pain, diarrhea, surgical removal of a single gastrinoma attempted, no evidence that it has spread to other organs, lymph nodes, liver, surgery on the stomach, gastrectomy, to control acid production is rarely necessary today, early diagnosis, surgical resection is associated, a cure rate of only 20% to 25%, gastrinomas grow slowly, patients, live, many years, tumor is discovered, acid-suppressing medications, very effective at controlling the symptoms of acid overproduction, spread, the tumor to other organs, most often liver, lymph nodes, failure to locate the tumor, surgery, intestinal bleeding, perforation from ulcers, in the stomach, duodenum, severe diarrhea, weight loss, severe, persistent abdominal pain occurs, occurs, diarrhea.